Aldous Huxley predicted antidepressants 20 years before studies began on them.
In his 1931 novel Brave New World, Huxley describes a mind-altering drug the people of London take in 2540 to retain their sanity. “Soma” is described as having “raised quite the impenetrable wall between the actual universe and their minds.” It wasn’t until the early 1950’s that research into the reality of these sorts of drugs caught on.