We can safely say that the friendship of Jen and Courtney is one of the strongest and most sincere friendships in Hollywood. The ladies met on the set of the popular show Friends in 1994 and became real-life besties. Though the actresses have gone through many difficulties (Cox’s divorce from David Arquette and Aniston’s divorce from Brad Pitt), they never cease to support and encourage each other in everything. In one of her interviews, Aniston revealed, "I’ve slept in her guest bedroom a lot. All I can say is she’s been there for me through thick and thin."