She starred on "Little House on the Prairie" as Jenny Wilder in the '80s and landed the major film "Heathers" in 1988. After she left "Beverly Hills, 90210" after its fourth season, she did smaller projects until being cast as one of the lead witches on the hit show, "Charmed."

She reprised her role as Brenda on "90210," a spin-off of the original show. Doherty later competed on "Dancing With the Stars" and is currently filming the TV Land reboot of "Heathers."

Doherty was diagnosed with Crohn's disease in 1999 and diagnosed with breast cancer in 2015. After years of battling the disease, she has been in remission since April 2017.