Nick Nolte and Julia Roberts
They first clashed on the set of “I Love Trouble” in 1994, and apparently things never got better. Sources say their mutual distaste for one another resulted in bad on-screen chemistry, and they had to shoot some of their scenes separately. Roberts called Nolte “Completely disgusting” and Nolte responded with “ She’s not a nice person, everyone knows that.” 15 years later in a 2009 interview on David Letterman, Roberts performed an ‘impression’ of a former co-star throwing a major temper tantrum, and no one was surprised when it turned out to be Nolte.