Matthew Perry had a slew of guest appearances and roles on short-lived sitcoms before nailing it as Chandler Bing on "Friends."
He earned two Emmy nominations for guest appearances on "The West Wing," as well as another nomination for the TV movie "The Ron Clark Story." Perry played an older Zac Efron in the teen movie "17 Again."
Since "Friends," he has struggled to find another sitcom that worked. His comedies "Mr. Sunshine" and "Go On" were both short-lived, but "The Odd Couple" lasted three seasons. His most recent role was playing Ted Kennedy on "The Kennedys: After Camelot."