Jessica Chastain
The actress was a frontrunner to win for her role in "Zero Dark Thirty" in 2013, but lost to Jennifer Lawrence for her role in "Silver Linings Playbook." Her other nomination was in 2012 for her supporting role in "The Help." She lost that one to her costar Octavia Spencer. In 2018, she'll likely get a nomination for her role in "Molly's Game." She probably won't win since it's a tough category this year, but she'll will get her Oscar some day, hopefully soon.