Saw (2004)
A controversial choice, sure, but what the original film did with that dirty bathroom can’t be overstated. I’ve seen a lot of horror films in my day, and the twist in the end just fucked with my head.
The rest of the films didn’t live up to the promise of the original, but for the hour and a half that you’re watching the two men try to figure out why they’re chained in a bathroom, you really feel the isolation and terror.
Again, it’s a testament to how fantastic a film can be with a limited budget, but tons of creativity and imagination.