Zach Braff — Scrubs
The sitcom about young doctors that often find themselves in different funny situations in the hospital started in 2001. The fans loved the character so much that the show aired until 2010. By the way, Zach Braff and Donald Faison, who played the main parts in the series, are good friends in real life. Braff is now 45 years old and Faison is 46.