Eddie Murphy As Prince Akeem, Clarence, Randy Watson, And Saul In Coming To America (1988)
Eddie Murphy is known for being somewhat of a master of all trades when it comes to acting—besides Coming to America from 1988, he was also responsible for at least 2 roles in Bowfinger (1999), The Adventures of Pluto Nash (2002), Norbit (2007), Meet Dave (2008), as well as the man behind a whopping 7 roles in The Nutty Professor (1996) and Nutty Professor II: The Klumps (2000).
Also, Arsenio Hall is responsible for a number roles in Coming to America, including Semmi, Morris, and Reverend Brown.