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In order to prepare for the main role on The Theory of Everything, Eddie Redmayne lost almost 15 pounds and was training to contort his body for 4 months to be able to move like people suffering from the same motor neuronal disease. Redmayne would stand in front of the mirror for hours, learning to contort his face correctly. Also, he kept hunching over between takes. Eventually, according to his osteopath, the actor had altered the alignment of his spine.
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