The Airlander, a hybrid airship developed by British aeronautical firm Hybrid Air Vehicles (HAV), is one of the largest aircrafts in the world. It was selected by the United States Army to provide intelligence, surveillance and reconnaissance support for ground troops. But they cancelled the project for cost reasons in February 2013.
 

There is a vast world of domesticated and wild hybrid animals that look pretty darn cool.

These mash-ups are fun and nicely made.