One of the many reasons that Punky Brewster was cancelled is because the star of the show, Soleil Moon Frye suffered from a condition called gigantomastia, literally giant breasts, and had a breast reduction surgery prior to her 16th birthday to reduce her 38DD to a more manageable size. The actress developed so quickly and so large that the producers felt there was no way they could reasonably portray her character age-appropriately.