"Seinfeld" (1989-1998)
Jerry Seinfeld and Larry David's creation launched a thousand quips — "shrinkage," "the jerk store called," "yada yada yada" — and might be the most important show in all of pop culture. Seinfeld's semi-autobiographical role was a template for Louis C.K. in "Louie" and Aziz Ansari in "Master of None," and the show is durable enough to be a persistent presence in meme culture.