"Futurama" (1999-2013)

Like "The Simpsons," "Futurama" was made by Matt Groening. Unlike its earthbound cousin, it was perennially under threat of cancellation. That isn't a reflection on its quality, though. "Futurama" — which followed the adventures of Philip J. Fry, a pizza delivery man who gets cryogenically frozen and wakes up 3,000 years later to join a misfit family of mutants, aliens, and robots — is just as clever. It also packs an emotional punch, not shying from the tragedy of what it's like to live a life a millennium after everyone you ever knew died.