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Jesse Williams as Jackson Avery

First episode (2009): "Invasion" (Season 6, Episode 5)

Latest episode (2020): "Put on a Happy Face" (Season 16, Episode 21)

What he's up to now (2020): Of course, Jesse is still on Grey's playing Jackson Avery, and he's directed three episode. He also appeared on Hulu's Little Fires Everywhere this year.

 

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“Grey’s Anatomy” Cast 15 Years Ago And Now
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