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Caterina Scorsone as Amelia Shepherd

First episode (2010): "Superfreak" (Season 7, Episode 3)

Latest episode (2020): "Put on a Happy Face" (Season 16, Episode 21)

What she's up to now (2020): Alongside her work on Grey's, Caterina played Amelia on Private Practice from 2010 to 2013 — between the two shows, she's actually appeared as Amelia in 211 episodes and counting.

 

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“Grey’s Anatomy” Cast 15 Years Ago And Now
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