Kate Walsh as Addison Montgomery
First episode (2005): "Who's Zoomin' Who?" (Season 1, Episode 9)
Last episode (2012): " If/Then" (Season 8, Episode 13)
What she's up to now (2020): Of course, Kate went on to star in Private Practice from 2007 to 2013 while still appearing in Grey's episodes. Since leaving the Grey's Anatomy universe, Kate has appeared in 13 Reasons Why, The Umbrella Academy, Girls Trip, and numerous other TV shows and movies. Also, she recently celebrated Addison's iconic first episode, which first aired 15 years ago.