Previously, Shawn Wayans had appeared in the comedy film saga, Scary Movie, which mocked typical horror films. After his participation in White Chicks, he made another film with his brother, Marlon Wayans, called Little Man. He’s currently a stand-up comedian and he does live performances. On the big screen, the last film he starred in was Dance Flick in 2009, for which he also wrote the screenplay.

Before acting in White Chicks, Rochelle Aytes had small television appearances on various shows including The Outer Limits and Sex and the City. Years later, she landed lead roles in shows such as FOX’s Drive in 2007 and The Forgotten in 2009 to 2010. Among her most recent work is her performance as Michelle Moore in the 2019 series, The Purge.

After her participation in White Chicks, the actress had small roles in television series such as Rules of Engagement, but she eventually left this branch of the entertainment industry.

After the premiere of this film, Jennifer Carpenter landed the lead role in the movie, The Exorcism of Emily Rose and the important role in the TV series, Dexter, as the main character’s sister. In 2016, she was part of the series Limitless, and in 2019, she played the lead role in The Enemy Within. She has also been a voice actress for various animated series with characters such as Natasha Romanova/Black Widow for Avengers Confidential: Black Widow & Punisher; Selina Kyle in Batman: Gotham by Gaslight; and Sonya Blade in Mortal Kombat Legends: Scorpion’s Revenge.

After participating in White Chicks, Busy Philipps brought Melissa’s character to life in Made of Honor in 2008, and also acted in He’s Just Not That into You, a romantic comedy from 2009. In the film industry, her most recent movie was I Feel Pretty in 2018. She has appeared in several series such as Cougar Town, Terminator: The Sarah Connor Chronicles, How I Met Your Mother, and ER. Between 2018 and 2019 she also had her own late-night show called Busy Tonight, which aired on E!.

Jessica Cauffiel remained active as an actress with films like Bed Ridden and Ice Dreams under her belt and was part of the cast of Legally Blonde, which announced its third installment in 2020. Legally Blonde 3 will mark Cauffiel’s return to the screen after she moved away from the spotlight in 2010. In the television world, she’s participated in the series My Name is Earl throughout 2006 and 2007.

Terry Crews appears in a lot of commercials, movies, and TV series. He was in the film Norbit with Eddie Murphy. He’s also part of the cast of The Expendables, which has already accumulated 3 installments, and he also appeared in the second part of Deadpool. On television, he played Julius in Everybody Hates Chris, and he’s one of the main characters in the series Brooklyn Nine-Nine.

Lochlyn Munro already had experience working with the Wayans family as he was part of the first Scary Movie that was released in 2000. He recently participated in different films such as A Stone Cold Christmas, Benchwarmers 2: Breaking Balls, Chokehold, Spiral, and Dead Voices. His career in television is extensive, as he’s participated in CSI: Miami, Smallville, The Mentalist, and Hawaii Five-0 between 2005 and 2012. Some of his most recent performances have been in Lucifer, Riverdale, and the Canadian series, The Murders.

Frankie Faison’s previous work before appearing in White Chicks includes The Silence of the Lambs (1991), Hannibal (2001), and Red Dragon (2002) from the Hannibal Lecter franchise. His last film was The Grudge, which was released in 2020 — he played the role of William Matheson. On television, his most emblematic role was that of Ervin Burrell in HBO’s The Wire. He also participated in the Netflix series Luke Cage, playing Henry “Pop” Hunter, a retired gangster who works in the same hair salon as the main character.

Marlon Wayans is still active as an actor, and his latest films, Naked and Sextuplets, have also been comedic hits. In conjunction with his brother, Shawn, he created a comic book company called 5-D Comics in 2006. In 2020, he announced the upcoming films, Respect, which is about the life of Aretha Franklin, and a comedy directed by Sofia Coppola called On the Rocks, which will star Bill Murray and Rashida Jones.