Sisters Kimberly Williams-Paisley and Ashley Williams:

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Kimberly starred in Father of the Bride and is married to Brad Paisley, and Ashley starred on How I Met Your Mother.

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Sisters Debbie Allen and Phylicia Rashad:

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You know Debbie from Grey's Anatomy (among other things) and Phylicia from The Cosby Show and, more recently, the Creed movies.

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Brother and sister Kevin Dunn and Nora Dunn:

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You probably know Nora from Saturday Night Live and Kevin from Veep.

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Brother and sister Tim Daly and Tyne Daly:

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You probably know Tim from Wings or, more recently, Private Practice. Tyne you might recognize just as a famous person you know of but don't know from exactly where.

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Sister and brother Abigail Breslin and Spencer Breslin:

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You know Spencer from tons of kids movies and Abigail from Little Miss Sunshine and also the new movie Stillwater.

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Brother and sister Jonah Hill and Beanie Feldstein:

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You know Beanie from Booksmart and Jonah from...lots of things.

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Brother and sister Jesse Eisenberg and Hallie Eisenberg:

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You probably remember Hallie best as the little Pepsi girl, and you know Jesse from The Social Network.

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Sister and brother Shirley MacLaine and Warren Beatty:

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They are both Hollywood legends.

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Sister and brother Tracee Ellis Ross and Evan Ross:

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You know Tracee from Black-ish, and Evan probably because he's married to Ashlee Simpson.

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Sisters Vera Farmiga and Taissa Farmiga:

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You probably recognize Vera from The Conjuring movies and Taissa from American Horror Story.

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Sister and brother Brandy and Ray J:

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You know Brandy because she's Brandy, and Ray J from his music and because he dated Kim Kardashian West a long time ago.

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Sister and brother Lily Allen and Alfie Allen:

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You know Lily because she's a singer, and Alfie for starring in Game of Thrones.

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Sister and brother Blake Lively and Eric Lively:

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You know Blake Lively because she's Blake Lively, and perhaps, if you watched The L Word, you'll recognize Eric as the creepy dude who lived with Shane and Jenny.

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Ilana Glazer and Eliot Glazer:

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You know Ilana from Broad City and might recognize Eliot from various small roles, but he also wrote for Younger and New Girl.

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Brother and sister Haley Joel Osment and Emily Osment:

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You know Haley as the kid from The Sixth Sense and Emily from Hannah Montana.

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John Turturro and Nicholas Turturro:

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You might recognize Nicholas from a variety of cop shows, including Blue Bloods and Law & Order, and maybe you know John from my personal-favorite role of his, Emilio in Mr. Deeds.

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Sisters Michelle Pfeiffer and Dedee Pfeiffer:

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Michelle is definitely the more well-known sister, but if you watch Big Sky, you'll recognize Dedee from that show.

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Sister and brother Florence Pugh and Toby Sebastian:

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You might remember Toby as Trystane Martell on Game of Thrones, and you know Florence from Black Widow and Midsommar.

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Sister and brother Alexandra Daddario and Matthew Daddario:

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You know Matthew from Shadowhunters and Alexandra from The White Lotus.

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Brothers Ralph Fiennes and Joseph Fiennes:

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Ralph is Voldemort, and Joseph is on The Handmaid's Tale.

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Brother and sister Wyatt Russell and Kate Hudson:

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Wyatt just starred in Marvel's The Falcon and the Winter Soldier TV show, and Kate Hudson is Kate Hudson.

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Alexander Skarsgård and Bill Skarsgård:

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You know Alexander Skarsgård because he's Alexander Skarsgård, and you know Bill as the Clown from It.

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